Piperonyl Methyl Ketone

$225.00$1,250.00

Piperonyl methyl ketone is a precursor or intermediate in the synthesis of methylenedioxy phenethylamines and amphetamines, including 3,4-MDMA (Item No. 13971). 1. It can be present as an impurity in preparations of methylenedioxy phenethylamines. PMK.

Clear

Description

Description about piperonyl methyl ketone?
3,4-Methylenedioxyphenylpropan-2-one or piperonyl methyl ketone is a chemical compound consisting of a phenylacetone moiety substituted with a methylenedioxy functional group. It is also called PMK.

A precursor or intermediate in the synthesis of methylenedioxy phenethylamines and amphetamines, including 3,4-MDMA
Piperonyl methyl ketone is a precursor or intermediate in the synthesis of methylenedioxy phenethylamines and amphetamines, including 3,4-MDMA. It can be present as an impurity in preparations of methylenedioxy phenethylamines. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.

Synonyms or Other Names
MDP2P
Piperonyl methyl ketone
3,4-Methylenedioxyphenylacetone
3,4-Methylenedioxyphenyl-2-propanone
PIPAC
PMK

Piperonyl methyl ketone is a precursor or intermediate in the synthesis of methylenedioxy phenethylamines and amphetamines, including 3,4-MDMA (Item No. 13971).1 It can be present as an impurity in preparations of methylenedioxy phenethylamines.2 The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.

product image (CAS 4676-39-5)

Piperonyl Methyl Ketone Specification
This chemical is called Piperonyl Methyl Ketone. With the CAS registry number 4676-39-5, it is also named as -(Acetonyl)-3,4-methylenedioxybenzene. The product’s category is Aromatic Ketones (substituted). Besides, it is yellow oily liquid. In addition, its molecular formula is C10H10O3 and molecular weight is 178.18.

Physical properties about Piperonyl Methyl Ketone are:  (1)ACD/LogP: 1.726; (2)ACD/LogD (pH 5.5): 1.73; (3)ACD/LogD (pH 7.4): 1.73; (4)ACD/BCF (pH 5.5): 12.07; (5)ACD/BCF (pH 7.4): 12.07; (6)ACD/KOC (pH 5.5): 206.99; (7)ACD/KOC (pH 7.4): 206.99; (8)#H bond acceptors: 3; (9)#Freely Rotating Bonds: 2; (10)Index of Refraction: 1.547; (11)Molar Refractivity: 46.626 cm3; (12)Molar Volume: 147.055 cm3; (13)Polarizability: 18.484 10-24cm3; (14)Surface Tension: 46.5340003967285 dyne/cm; (15)Density: 1.212 g/cm3; (16)Flash Point: 111.373 °C; (17)Enthalpy of Vaporization: 51.44 kJ/mol; (18)Boiling Point: 275.92 °C at 760 mmHg; (19)Vapour Pressure: 0.00499999988824129 mmHg at 25°C

Preparation of Piperonyl Methyl Ketone: this chemical is commonly synthesized from either safrole or its isomer isosafrole via oxidation using the Wacker oxidation or peroxyacid oxidation methods. Similarly, it can be prepared by 5-(3-Methyl-oxiranyl)-benzo[1,3]dioxole.

This reaction needs Tetrahydrofuran and Hexane at ambient temperature. The yield is 90 %.

Uses of Piperonyl Methyl Ketone:

This chemical is used as pharmaceutical intermediate. It is also used for the synthesis of berberine, methyl dopa, antihypertensive and anti-tumor drugs. Moroever, it can react with 2-Formyl-benzoic acid to get 3-(1-Benzo[1,3]dioxol-5-yl-2-oxo-propyl)-3H-isobenzofuran-1-one.

Application of PMK
Metabolite of 3,4-Methylenedioxyethylamphetamine (MDE) and 3,4-(Methylenedioxy)methamphetamine (MDMA).

Piperonyl methyl ketone is a precursor or intermediate in the synthesis of methylenedioxy phenethylamines and amphetamines, including 3,4-MDMA (Item No. 13971). It can be present as an impurity in preparations of methylenedioxy phenethylamines.

he classic ‘ketone’ approach (certainly not the only possibility, but the best documented one) has a lot of variations, but the basic scheme is the oxidation of the plant oil safrole (1-allyl-3,4-methylenedioxybenzene) into a ketone (3,4-methylenedioxyphenyl-2-propanone), which is then condensed with methylamine and reduced to the final MDMA product. Contact Us.

Additional information

Quantity

2.5L, 5L, 10L, 15L, 20L, 25L

Reviews

There are no reviews yet.

Be the first to review “Piperonyl Methyl Ketone”

Your email address will not be published. Required fields are marked *

X